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Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...

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Related Experiment Video

Updated: May 19, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
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Published on: February 2, 2021

Renal replacement therapy in ICU.

C Deepa1, K Muralidhar

  • 1Narayana Hrudayalaya, Bangalore, Karnataka, India.

Journal of Anaesthesiology, Clinical Pharmacology
|August 8, 2012
PubMed
Summary
This summary is machine-generated.

Critically ill patients with acute kidney injury often require renal replacement therapy (RRT). This therapy is crucial for managing renal failure and extends to treating conditions like septic shock in the ICU.

Keywords:
Acute kidney insufficiencyCRRTCVVHICUIHDSLEDDacute renal failureanticoagulationperitoneal dialysisrenal replacement therapy

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Published on: November 21, 2025

Area of Science:

  • Critical Care Medicine
  • Nephrology
  • Intensive Care Unit (ICU) Management

Background:

  • Renal dysfunction is common in critically ill patients, significantly impacting morbidity and mortality.
  • Acute kidney insufficiency presents a major challenge in intensive care settings.
  • Effective management of renal dysfunction is essential for patient outcomes.

Purpose of the Study:

  • To outline the critical role of renal replacement therapy (RRT) in the intensive care unit (ICU).
  • To highlight the application of RRT beyond traditional renal failure management.
  • To provide an overview for intensivists on utilizing RRT in complex cases.

Main Methods:

  • Review of current literature on renal replacement therapy in critical care.
  • Discussion of RRT applications in various critical conditions.
  • Synthesis of information relevant to intensivist practice.

Main Results:

  • Renal replacement therapy (RRT) is a cornerstone in managing acute and chronic renal failure in ICU patients.
  • RRT demonstrates efficacy in treating non-renal conditions such as myasthenia gravis, septic shock, and acute-on-chronic liver failure.
  • The application of RRT is expanding, offering therapeutic benefits in diverse critical illnesses.

Conclusions:

  • Renal replacement therapy (RRT) plays a vital role in the management of critically ill patients with renal dysfunction.
  • The utility of RRT extends to treating a spectrum of critical conditions beyond primary kidney failure.
  • Intensivists must be adept at employing RRT for both renal support and as a therapeutic modality for other organ failures.