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Updated: May 19, 2026
Multiplex Immunohistochemistry Staining for Paraffin-embedded Lung Cancer Tissue
Published on: November 21, 2023
Digital ischemia as a paraneoplastic consequence of squamous cell lung carcinoma
Adedayo A Onitilo1, Jennifer Demos-Bertrand, Jill Depke
1Department of Hematology/Oncology, Marshfield Clinic Weston Center, 3501 Cranberry Blvd, Weston, WI 54476, USA. onitilo.adedayo@marshfieldclinic.org
Abstract:
We report the case of a 40-year-old man who presented with digital ischemia and squamous cell lung carcinoma. Based on review of the literature, to our knowledge this case represents the youngest patient with lung carcinoma associated with digital ischemia and the only one with this type of tumor. The patient's digital ischemia symptoms improved rapidly with systemic chemotherapy; however, he did eventually lose the distal portion of 1 finger to dry gangrene and mummification.