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Related Concept Videos

Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
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IR Spectrometers

There are two main infrared (IR) spectrophotometers: dispersive IR spectrometers and Fourier transform infrared (FTIR) spectrometers. In a dispersive IR spectrometer, a beam of infrared radiation produced by a hot wire is divided into two parallel equal-intensity beams using mirrors. One beam passes through the sample, while another is a reference beam. The beams then move through the monochromator, which separates the radiations into a continuous spectrum of different frequencies. The...
Two-Dimensional (2D) NMR: Overview01:12

Two-Dimensional (2D) NMR: Overview

The 1D NMR spectrum of large and complex molecules like natural products has complicated splitting patterns and overlapping signals, which can be easily interpreted using 2-dimensional (2D) NMR. Unlike 1D NMR, 2D NMR has two frequency axes that provide the coupling information between the nucleus A and nucleus B in a molecule. The process from which 2D spectra are obtained has four steps.
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2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)01:19

2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)

Heteronuclear single-quantum correlation spectroscopy (HSQC) is a 2D NMR technique that reveals one-bond correlations between hydrogen and a heteronucleus. The HSQC experiment is similar to the heteronuclear correlation experiment (HETCOR) but is more sensitive. In the HSQC spectrum, the proton chemical shift is plotted on the horizontal F2 axis, while the 13C chemical shift is plotted on the vertical F1 axis. The corresponding proton and 13C spectra are also shown. The HSQC contour plot does...
UV–Vis Spectrometers01:14

UV–Vis Spectrometers

The absorbance of UV and visible (UV–visible) radiations is measured using a UV–visible spectrophotometer. Deuterium lamps, which emit UV radiation, and tungsten lamps, which produce radiation in the visible region, are used as light sources in UV–visible spectrophotometers. A monochromator or prism is used for diffraction grating, i.e., to split the incoming radiation into different wavelengths. A system of slits is used to focus the desired wavelength on the sample cell. Samples for...
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...

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A Multimodal Wide-Field Fourier-Transform Raman Microscope
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[A two-dimensional double dispersed hadamard transform spectrometer].

Jia Liu1, Lei Shi, Kai Li

  • 1School of Electronic Information, Wuhan University, Wuhan 430079, China. Liujiayp@yahoo.com.cn

Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu
|August 9, 2012
PubMed
Summary
This summary is machine-generated.

A novel two-dimensional Hadamard transform spectrometer utilizes a digital micromirror device for optical modulation, achieving higher resolution and signal-to-noise ratio than traditional methods. This advancement offers improved spectral analysis capabilities.

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Area of Science:

  • Spectroscopy
  • Optical Engineering
  • Instrument Development

Context:

  • Traditional spectrometers often face limitations in resolution and signal-to-noise ratio.
  • Existing spectral dispersion and detection methods can be complex and costly.

Purpose:

  • To develop a novel two-dimensional Hadamard transform spectrometer.
  • To improve spectral resolution and signal-to-noise ratio using a digital micromirror device (DMD).

Summary:

  • A two-dimensional Hadamard transform spectrometer was engineered using a grating for order dispersion and a prism for spectral dispersion.
  • A digital micromirror device (DMD) was employed for optical modulation, coupled with a simple point detector, deviating from conventional CCD detection.
  • Theoretical calculations and computer simulations validated the spectrometer's enhanced high resolution and signal-noise-ratio.

Impact:

  • This new spectrometer design offers superior performance compared to traditional two-dimensional spectrometers.
  • The use of DMD technology presents a potentially more cost-effective and efficient approach to spectral analysis.
  • The findings pave the way for advancements in various fields requiring high-fidelity spectral measurements.