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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...

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Related Experiment Video

Updated: May 19, 2026

Studies on the Anti-Inflammatory Effect of Xiaoyao Pills in The Treatment of Postmenopausal Osteoporosis in Mice
07:20

Studies on the Anti-Inflammatory Effect of Xiaoyao Pills in The Treatment of Postmenopausal Osteoporosis in Mice

Published on: August 23, 2024

[Osteoporosis and pharmaceutical care].

Kinga Kövér1, Agnes Mészáros

  • 1Semmelweis Egyetem, GYTK Egyetemi Gyógyszertár Gyógyszerügyi Szervezési Intézet H-1092 Budapest, Hőgyes Endre u. 7-9.

Acta Pharmaceutica Hungarica
|August 9, 2012
PubMed
Summary

Patient adherence to osteoporosis management is crucial for treatment effectiveness and cost-efficiency. Many patients face medication issues, highlighting the need for pharmaceutical care to improve long-term therapy adherence.

Area of Science:

  • Osteoporosis management
  • Patient adherence
  • Pharmaceutical care

Context:

  • Osteoporosis poses a growing global health challenge.
  • Effective management is vital for cost-effective treatment.
  • Patient compliance significantly impacts therapeutic outcomes.

Purpose:

  • To review existing literature on patient compliance in osteoporosis management.
  • To identify key challenges affecting patient adherence.
  • To explore the role of pharmaceutical care in improving adherence.

Summary:

  • A significant majority of patients (60%) experience medication-related problems.
  • Engaging patients actively in their disease management and maintaining persistence are significant challenges.
  • Pharmaceutical care aims to enhance patient-provider cooperation and long-term drug therapy adherence.

Related Experiment Videos

Last Updated: May 19, 2026

Studies on the Anti-Inflammatory Effect of Xiaoyao Pills in The Treatment of Postmenopausal Osteoporosis in Mice
07:20

Studies on the Anti-Inflammatory Effect of Xiaoyao Pills in The Treatment of Postmenopausal Osteoporosis in Mice

Published on: August 23, 2024

Impact:

  • Highlights the critical need for interventions to improve patient adherence in osteoporosis.
  • Suggests pharmaceutical care as a key strategy to overcome adherence barriers.
  • Emphasizes the link between adherence, health outcomes, and economic efficiency in osteoporosis treatment.