Related Experiment Video

Updated: May 19, 2026

A High-Throughput Comet Assay Approach for Assessing Cellular DNA Damage
07:57

A High-Throughput Comet Assay Approach for Assessing Cellular DNA Damage

Published on: May 10, 2022

Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay.

Peggy L Olive, Judit P Banáth, Ralph E Durand

    Radiation Research
    |August 9, 2012
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    CometChip: A High-throughput 96-Well Platform for Measuring DNA Damage in Microarrayed Human Cells
    10:59

    CometChip: A High-throughput 96-Well Platform for Measuring DNA Damage in Microarrayed Human Cells

    Published on: October 18, 2014

    Assaying DNA Damage in Hippocampal Neurons Using the Comet Assay
    10:00

    Assaying DNA Damage in Hippocampal Neurons Using the Comet Assay

    Published on: December 19, 2012

    Related Experiment Videos

    Last Updated: May 19, 2026

    A High-Throughput Comet Assay Approach for Assessing Cellular DNA Damage
    07:57

    A High-Throughput Comet Assay Approach for Assessing Cellular DNA Damage

    Published on: May 10, 2022

    CometChip: A High-throughput 96-Well Platform for Measuring DNA Damage in Microarrayed Human Cells
    10:59

    CometChip: A High-throughput 96-Well Platform for Measuring DNA Damage in Microarrayed Human Cells

    Published on: October 18, 2014

    Assaying DNA Damage in Hippocampal Neurons Using the Comet Assay
    10:00

    Assaying DNA Damage in Hippocampal Neurons Using the Comet Assay

    Published on: December 19, 2012

    Related Concept Videos

    Nucleotide Excision Repair01:38

    Nucleotide Excision Repair

    DNA Distortion and Damage
    Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
    Other Unique Bacteria01:18

    Other Unique Bacteria

    Magnetic bacteria exhibit a directed movement called magnetotaxis, driven by structures called magnetosomes. These magnetosomes consist of chains of magnetic particles made of either magnetite (Fe₃O₄) or greigite (Fe₃S₄) and are organized in a linear conformation by a protein scaffold within invaginations of the cell membrane. The bacteria align along the north–south magnetic field lines, much like a compass needle. They are typically microaerophilic or anaerobic and are commonly found near the...

    Articles linked to this work by shared authors, journal, and citation graph.

    Radiation and Chemo-Sensitizing Effects of DNA-PK Inhibitors Are Proportional in Tumors and Normal Tissues.

    Molecular cancer therapeutics·2024

    DNA-PK inhibitor AZD7648 is a more portent radiosensitizer than PARP inhibitor Olaparib in BRCA1/2 deficient tumors.

    DNA repair·2024

    DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost.

    Scientific reports·2023

    Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs.

    Breast cancer research : BCR·2019

    Radiobiological intercomparison of the 160 MeV and 230 MeV proton therapy beams at the Harvard Cyclotron Laboratory and at Massachusetts General Hospital.

    Radiation research·2015

    Macrophages are more potent immune suppressors ex vivo than immature myeloid-derived suppressor cells induced by metastatic murine mammary carcinomas.

    Journal of immunology (Baltimore, Md. : 1950)·2013

    Lysophosphatidic Acid Receptor Activation Regulates Expression of the Immediate Early Gene IEX-1 in Irradiated Cells and Tissues.

    Radiation research·2026

    Low-dose Ionizing Radiation Induces Oxidative Stress through Sirtuin 1-mediated Acetylation of Forkhead Box Protein O1 in the Human B-lymphoblastoid Cell Line IM-9.

    Radiation research·2026

    Glutamine, a Potential Metabolomic Biomarker and Therapeutic Target in Radiation-induced Liver Damage.

    Radiation research·2026

    Influence of Cell Size Changes after Irradiation on Reliability of an Impedance Measurement-based Hematology Analyzer.

    Radiation research·2026

    Radiomic Prediction of Locally Advanced Cervical Squamous Cell Carcinoma Response to Concurrent Chemoradiotherapy using MRI.

    Radiation research·2026

    CXCR2 Blockade Improves Response to Hypo-fractionated Radiation Treatment in a Murine Head and Neck Squamous Cell Carcinoma (HNSCC) Model.

    Radiation research·2026

    Distinct ecological patterns of abundant and rare prokaryotic taxa across sediment and water habitats in an acid mine drainage-impacted river system.

    Environmental geochemistry and health·2026

    Estimating marine PM2.5 concentrations and exploring the drivers over the eastern China seas using multi-source data and machine learning.

    Environmental pollution (Barking, Essex : 1987)·2026

    Integrated modelling framework for predicting microplastic build-up on urban surfaces.

    Journal of hazardous materials·2026

    Assessing the removal of microplastics, nanoplastics, and tire derived contaminants using chemically enhanced primary treatment.

    Journal of hazardous materials·2026

    Hydrological regime controls DOM and WEOM dynamics in contrasting mid-channel bars: Insights from the middle Yangtze River.

    Water research·2026

    Ultrafast micropollutant degradation via reductive activation of periodate under VUV/UV (185/254 nm) irradiation beyond photolysis.

    Water research·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us