Recent advances in the chemistry of SmI(2)-H(2)O
Brice Sautier1, David J Procter
1University of Manchester, School of Chemistry, Oxford Road, Manchester M13 9PL, UK.
Chimia
|August 9, 2012
Abstract:
Recent work from our laboratories has shown SmI(2)-H(2)O to be a versatile, readily-accessible and non-toxic reductant that is more powerful than SmI(2). This review describes the reduction of functional groups that were previously thought to lie beyond the reach of SmI(2) and complexity-generating cyclisations and cyclisation cascades triggered by the reduction of the ester carbonyl group with SmI(2)-H(2)O.
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