Analysis of macro- and microstructures of normal and pathological tissues by ultrasonic backscattering techniques

A technique to obtain the spacing distribution of macro- and microstructures of hypercholestrolemic liver, lymphoidlucosed liver, rhinosporidium of man and ethmoidal tumour of bovine is presented. The method uses signal processing of spatially averaged spectra of ultrasonic backscattering from tissues in the frequency range 2-8 MHz. The macrostructure is obtained from signal processing of spectral modulation amplitude and the microstructure from the frequency dependence of backscattering coefficient. The results obtained show good correlation with tissue histologies.