Does ionizing radiation influence Alzheimer's disease risk?
Related Experiment Video
Updated: May 19, 2026

Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining
Published on: May 23, 2025
Nasrin Begum1, Bing Wang, Masahiko Mori
1Center for Nuclear Medicine and Ultrasound, Rajshahi Medical College Hospital Campus, GPO Box No. 35, Rajshahi, Bangladesh.
Abstract:
Alzheimer's disease (AD) is a human neurodegenerative disease, and its global prevalence is predicted to increase dramatically in the following decades. There is mounting evidence describing the effects of ionizing radiation (IR) on the brain, suggesting that exposure to IR might ultimately favor the development of AD. Therefore better understanding the possible connections between exposure to IR and AD pathogenesis is of utmost importance. In this review, recent developments in the research on the biological and cognitive effects of IR in the brain will be explored. Because AD is largely an age-related pathology, the effects of IR on ageing will be investigated.
Related Concept Videos
Alzheimer Disease l: Introduction
Alzheimer Disease ll: Pathophysiology
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Biological Effects of Radiation
Alzheimer's Disease: Treatment
Psychoneuroimmunology: Diabetes and Cancer