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Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
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Occupational asthma in Japan.

Kunio Dobashi1

  • 1Gunma University School of Health Sciences, Maebashi, Gunma 371-8514, Japan.

Asia Pacific Allergy
|August 9, 2012
PubMed
Summary
This summary is machine-generated.

Occupational asthma (OA) research in Japan has seen reductions in some types, like konjac asthma, but chemical-induced cases are rising. Current focus on medical treatment may neglect identifying the specific causes of OA.

Keywords:
Allergic asthmaEnvironmentOccupational asthmaWorkplace

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Area of Science:

  • Allergy and Immunology
  • Occupational Health
  • Environmental Medicine

Background:

  • Research on occupational asthma (OA) in Japan is primarily led by the Japanese Society of Occupational and Environmental Allergy.
  • Early reports identified specific allergens like konjac, leading to successful reduction efforts for certain OA types (e.g., konjac, sea squirt asthma).
  • Recent technological advancements have led to an increase in chemical antigen-induced asthma cases within Japan.

Purpose of the Study:

  • To discuss the current status of occupational asthma in Japan.
  • To highlight the shift in focus from identifying causative antigens to managing symptoms with advanced medications.
  • To address the lack of established Japanese guidelines for OA diagnosis and management.

Main Methods:

  • Review of existing research and reports on occupational asthma in Japan.
  • Analysis of trends in OA prevalence, including specific types like konjac and chemical-induced asthma.
  • Discussion of current diagnostic and management approaches in the context of advancing medical treatments.

Main Results:

  • Significant reduction in cases of konjac asthma and sea squirt asthma due to medical interventions.
  • A notable increase in occupational asthma triggered by chemical antigens, correlating with technological development.
  • Emphasis on medical treatment control for asthma, potentially overshadowing the identification of causative agents.
  • Absence of a national guideline for the diagnosis and management of occupational asthma in Japan.

Conclusions:

  • While some occupational asthma types have decreased, chemical-induced cases are a growing concern in Japan.
  • There is a need to re-emphasize the identification of causative antigens in occupational asthma.
  • Development and implementation of a Japanese guideline for occupational asthma are crucial for effective diagnosis and management.