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Related Concept Videos

Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...

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Related Experiment Video

Updated: May 19, 2026

A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation
06:50

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Published on: June 10, 2020

Do traumatic brain contusions increase in size after decompressive craniectomy?

Carmelo Lucio Sturiale1, Pasquale De Bonis, Luigi Rigante

  • 1Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.

Journal of Neurotrauma
|August 10, 2012
PubMed
Summary
This summary is machine-generated.

Decompressive craniectomy (DC) does not appear to increase the risk of hemorrhagic contusion (HC) evolution after traumatic brain injury (TBI). Our study found no significant difference in HC growth between patients treated with DC and those receiving only medical therapy.

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Area of Science:

  • Neurosurgery
  • Trauma Surgery
  • Radiology

Background:

  • Hemorrhagic contusions (HC) are common after traumatic brain injury (TBI).
  • The evolution of HC and the impact of decompressive craniectomy (DC) remain unclear.
  • Understanding HC evolution is crucial for TBI management.

Purpose of the Study:

  • To investigate the effect of DC on the evolution of post-traumatic HC.
  • To determine if DC is a risk factor for HC enlargement or new appearance.

Main Methods:

  • Retrospective analysis of 57 TBI patients with initial HC.
  • Comparison between 25 patients undergoing DC (Group 1) and 32 receiving medical therapy alone (Group 2).
  • Logistic regression used to identify predictive factors for HC evolution.

Main Results:

  • No significant difference in HC volume increase (≥2 cc) between DC and medical therapy groups (16% vs. 12.5%, p=0.72).
  • No identified factors, including DC, were significantly associated with HC evolution or de novo appearance.
  • HC evolution occurred in 14% of all analyzed patients.

Conclusions:

  • Decompressive craniectomy does not appear to be a risk factor for the evolution or de novo appearance of hemorrhagic contusions in TBI patients.
  • Current findings suggest DC can be safely considered in TBI management without exacerbating HC progression.