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Related Experiment Videos

Interhemispheric fissure width in neonates on ECMO.

D A Rubin1, G W Gross, S M Ehrlich

  • 1Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.

Pediatric Radiology
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

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Interhemispheric (IHF) widening in infants on ECMO often parallels body edema development. This intracranial finding typically resolves after ECMO support is withdrawn.

Area of Science:

  • Pediatric critical care medicine
  • Neonatal neuroimaging
  • Extracorporeal membrane oxygenation (ECMO) research

Background:

  • Infants undergoing ECMO support are susceptible to fluid overload and generalized edema.
  • Intracranial changes associated with ECMO-related edema are not fully understood.
  • Neurosonography offers a non-invasive method to assess intracranial dynamics.

Purpose of the Study:

  • To investigate the relationship between interhemispheric (IHF) width changes and the development of generalized body edema in infants on ECMO.
  • To determine if IHF widening is a marker for ECMO-associated edema.
  • To assess the reversibility of IHF widening after ECMO cessation.

Main Methods:

  • Retrospective review of neurosonograms from 58 infants receiving ECMO support.

Related Experiment Videos

  • Categorization of patients based on patterns of body edema development (chest wall thickening on radiographs).
  • Comparison of IHF width changes with edema severity and chest wall thickening.

    • Main Results:

    • A progressive increase in IHF width was observed during ECMO support.
    • The pattern of IHF widening correlated with the development and severity of generalized body edema.
    • IHF widening resolved upon discontinuation of ECMO support, confirmed by follow-up cranial CT.

    Conclusions:

    • Interhemispheric (IHF) widening during ECMO in infants is likely an intracranial manifestation of systemic fluid accumulation and generalized edema.
    • Neurosonographic monitoring of IHF width may serve as a non-invasive indicator of ECMO-related edema.
    • The reversibility of IHF widening suggests a dynamic relationship between systemic fluid balance and intracranial parameters in neonates on ECMO.