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Published on: June 16, 2020
Drug compliance in patients with systemic scleroderma
Lucie Hromadkova1, Tomas Soukup, Eva Cermakova
1Department of Social and Clinical Pharmacy, Faculty of Pharmacy, Charles University in Prague, Heyrovskeho 1203, Hradec Kralove 500 05, Czech Republic. lucie.hromadkova@faf.cuni.cz
This study found that only 42% of systemic scleroderma patients have adequate drug compliance. Common risk factors for noncompliance were not identified, suggesting individual patient factors are key.
Area of Science:
- Rheumatology
- Pharmacology
- Patient Adherence Studies
Background:
- Drug compliance is vital for chronic disease treatment effectiveness.
- Compliance has not been previously assessed in systemic scleroderma patients.
Purpose of the Study:
- To determine the drug compliance rate in systemic scleroderma patients.
- To identify potential risk factors associated with noncompliance in this population.
Main Methods:
- A cross-sectional observational study design was employed.
- Data collected via structured interviews and medical records from 41 systemic scleroderma patients.
- The Compliance Questionnaire Rheumatology (CQR) assessed patient compliance.
Main Results:
- The mean CQR score was 75%, indicating suboptimal compliance.
- Only 42% of patients met the satisfactory compliance threshold (≥80%).
- No significant relationships were found between compliance and demographic or clinical characteristics.
Conclusions:
- This is the first study evaluating drug compliance in systemic scleroderma.
- A significant proportion of patients exhibit noncompliance.
- Common risk factors for noncompliance were not identified, highlighting the role of individual patient factors.
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