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SARS-CoV regulates immune function-related gene expression in human monocytic cells

Wanchung Hu1, Yu-Ting Yen, Sher Singh

  • 1Graduate Institute of Immunology, National Taiwan University College of Medicine, Taipei, Taiwan, ROC.

Viral Immunology
|August 11, 2012
PubMed
Summary

Severe acute respiratory syndrome coronavirus (SARS-CoV) alters immune cell gene expression. SARS-CoV infection downregulates key antiviral genes and upregulates hypoxia-related genes in monocytes, impacting SARS pathogenesis.

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