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Updated: May 19, 2026

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
Published on: July 4, 2007
Malaria model with periodic mosquito birth and death rates
Bassidy Dembele1, Avner Friedman, Abdul-Aziz Yakubu
1Department of Mathematics and Computer Science, Grambling State University, Grambling, LA, USA.
Abstract:
In this paper, we introduce a model of malaria, a disease that involves a complex life cycle of parasites, requiring both human and mosquito hosts. The novelty of the model is the introduction of periodic coefficients into the system of one-dimensional equations, which account for the seasonal variations (wet and dry seasons) in the mosquito birth and death rates. We define a basic reproduction number R(0) that depends on the periodic coefficients and prove that if R(0)<1 then the disease becomes extinct, whereas if R(0)>1 then the disease is endemic and may even be periodic.
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