Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Circadian Rhythms and Gene Regulation

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...

Circadian Rhythms and Gene Regulation

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...

Biological Clocks and Seasonal Responses

Biological Clocks and Seasonal Responses

The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Modelling the effect of V1a receptor antagonism and its potential therapeutic effect in circadian disorders.

Npj biological timing and sleep·2026

Same author

The effect of timing of physical exercise on glycemia: a systematic review and meta-analysis of human intervention studies.

Journal of diabetes and metabolic disorders·2026

Same author

Metabolic health effects of the timing of lifestyle behaviours in a combined lifestyle intervention in adults who have obesity or are overweight with complications: protocol for a two-armed, cluster-randomized, pragmatic trial-a TIMED study.

Trials·2026

Same author

Brain-wide induction of ΔFOSB and altered co-activation networks in a rat model for exercise training.

Translational psychiatry·2026

Same author

Missing the rhythm in skeletal muscle mitochondrial respiration.

American journal of physiology. Endocrinology and metabolism·2026

Same author

Targeted PPARδ activation reprograms microglial immunometabolism and improves insulin sensitivity in HFD-fed rats.

Journal of lipid research·2026

Search research articles

Related Experiment Video

Updated: May 19, 2026

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

Circadian rhythms in white adipose tissue.

Rianne van der Spek¹, Felix Kreier², Eric Fliers¹

¹Department of Endocrinology and Metabolism, Academic Medical Center (AMC), University of Amsterdam (UvA), Amsterdam, The Netherlands.

Progress in Brain Research

|August 11, 2012

Summary

This summary is machine-generated.

Adipose tissue regulates metabolism via adipokines with daily rhythms. Disruptions to these circadian rhythms are linked to metabolic diseases like obesity and type 2 diabetes.

More Related Videos

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Published on: March 28, 2013

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

Related Experiment Videos

Last Updated: May 19, 2026

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Published on: March 28, 2013

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

Area of Science:

Endocrinology
Metabolic Biology
Chronobiology

Background:

Adipose tissue functions as a key endocrine organ.
It secretes adipokines regulating appetite, glucose disposal, and energy expenditure.
Adipokines exhibit significant daily (circadian) rhythms.

Purpose of the Study:

To review the circadian system's role in adipose tissue biology.
To discuss white adipose tissue (WAT) development, characteristics, and innervation.
To explore the link between circadian rhythm disruption and obesity.

Main Methods:

Literature review of circadian biology.
Review of white adipose tissue development and function.
Synthesis of recent findings on circadian rhythms and metabolic disease.

Main Results:

Adipose tissue is crucial for energy metabolism regulation.
Circadian rhythms in adipokine secretion are vital.
Disruption of these rhythms is associated with obesity and type 2 diabetes.

Conclusions:

Circadian regulation is integral to adipose tissue function.
Understanding these rhythms is critical for addressing metabolic disorders.
Further research into circadian rhythms may reveal novel therapeutic targets for obesity.