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[Aortic valve stenosis is associated with reduced myocardial perfusion as assessed by videodensitometry in coronary

Ferenc Tamás Nagy1, Tamás Horváth, Tamás Ungi

  • 1Szegedi Tudományegyetem, Általános Orvostudományi Kar II. Belgyógyászati Klinika és Kardiológiai Központ, Invazív Kardiológiai Részleg és Hemodinamikai Laboratórium Szeged Korányi fasor 6. 6720.

Orvosi Hetilap
|August 11, 2012
PubMed

Insights

Patients with aortic valve stenosis show reduced myocardial perfusion, indicated by lower Gmax/Tmax values. This finding suggests microvascular abnormalities contribute to angina in these patients.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Vascular Physiology

Background:

  • Aortic valve stenosis (AVS) can cause angina, even with clear coronary arteries.
  • Microvascular abnormalities are suspected contributors to angina in AVS patients.

Purpose of the Study:

  • To assess myocardial perfusion using coronary angiogram densitometry in patients with AVS.
  • To determine if myocardial perfusion is reduced in AVS compared to controls.

Main Methods:

  • Coronary angiograms were analyzed in 20 AVS patients and 30 controls.
  • Myocardial perfusion was quantified using the Gmax/Tmax ratio from time-density curves.

Main Results:

  • Patients with AVS exhibited significantly lower mean three-vessel Gmax/Tmax values (2.55±1.02 1/sec) versus controls (3.39±1.09 1/sec).
  • This indicates reduced myocardial perfusion in AVS patients.

Conclusions:

  • Densitometry on coronary angiograms reveals reduced myocardial perfusion (Gmax/Tmax) in AVS patients.
  • These perfusion abnormalities correlate with microvascular dysfunction in AVS.
Abstract

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