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Updated: May 19, 2026
Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
Published on: September 2, 2025
Variability in knee laxity in anterior cruciate ligament deficiency using a mechanized model
Courtney K Dawson1, Eduardo M Suero, Andrew D Pearle
1Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USA. courtneykdawson@gmail.com
Purpose:
To establish normative values for the magnitude of anterior tibial translation (ATT) in the Lachman and pivot shift tests in the intact and anterior cruciate ligament (ACL)-deficient states, and to explore whether a correlation in ATT magnitude exists between the Lachman and pivot shift tests.
Methods:
Twenty-six fresh frozen cadaveric hip-to-toe specimens were used. Mechanized testing was performed to simulate both a Lachman and pivot shift test with the ACL intact. Tests were repeated after sectioning the ACL. ATT was recorded using a computer navigation system. Difference in ATT after sectioning was calculated for each specimen.
Results:
For the Lachman, mean lateral compartment ATT in the intact knee was 5.3 mm (SD = 2.8 mm). After sectioning the ACL, translation increased to 11.4 mm (SD = 3.9 mm; P < 0.05). For the mechanized pivot shift, mean lateral compartment ATT in the intact knee was -0.2 mm (SD = 2.6 mm). After sectioning the ACL, translation increased to 8.2 mm (SD = 3.1 mm; P < 0.05). No correlation in the magnitude of ATT was found between the intact and ACL-deficient knees for either the Lachman or pivot shift tests, or between both tests (Cronbach's α < 0.7).
Conclusions:
No correlation was found between the Lachman and pivot shift test in both the intact and ACL-deficient knee. This suggests that the Lachman cannot be used as a surrogate for the pivot shift as the magnitude of the Lachman did not predict the magnitude of the pivot shift.
