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Does circumcision alter the periurethral uropathogenic bacterial flora.

Mushtaq Ahmad Laway1, Mohd Lateef Wani, Rekha Patnaik

  • 1Department of Paediatric Surgery, Sheri-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, Kashmir, India.

African Journal of Paediatric Surgery : AJPS
|August 11, 2012
PubMed
Summary

Circumcision significantly alters periurethral bacterial flora in boys, reducing uropathogens and potentially preventing urinary tract infections (UTI). This supports early circumcision as a preventive measure for UTI.

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Area of Science:

  • Pediatric Urology
  • Microbiology
  • Public Health

Background:

  • The prepuce harbors a significant quantity of periurethral bacteria.
  • Uncircumcised boys show a higher likelihood of uropathogen colonization.
  • Urinary tract infections (UTI) are a concern in pediatric populations.

Purpose of the Study:

  • To assess the periurethral bacterial flora pattern in uncircumcised boys.
  • To evaluate the impact of circumcision on periurethral uropathogenic bacteria.
  • To explore the association between circumcision and UTI prevention.

Main Methods:

  • Prospective study of periurethral bacterial flora in 124 boys before and after circumcision.
  • Analysis of bacterial colonization changes pre- and post-circumcision.
  • Age range: 6 weeks to 96 months.

Main Results:

  • Common flora in uncircumcised boys: E. coli, Proteus, Klebsiella.
  • Common flora in circumcised boys: Coagulase-negative Staphylococcus, Staphylococcus aureus.
  • Sterile periurethral region observed in 66.1% of circumcised subjects.

Conclusions:

  • Presence of the prepuce is linked to increased periurethral bacteria and uropathogens.
  • Circumcision leads to a significant reduction in periurethral bacterial load.
  • Early circumcision may offer benefits in preventing urinary tract infections (UTI).