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Related Concept Videos

Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its effects by...
Stimulants01:29

Stimulants

Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Pharmaceutical Poisoning: Treatment Strategies01:26

Pharmaceutical Poisoning: Treatment Strategies

Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...

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Related Experiment Video

Updated: May 19, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
07:51

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder

Published on: June 18, 2018

[Treating cocaine addiction].

M Herdener1, R Oppliger, R Stohler

  • 1Zentrum für Abhängigkeitserkrankungen, Psychiatrische Universitätsklinik Zürich.

Praxis
|August 11, 2012
PubMed
Summary
This summary is machine-generated.

Effective treatments for cocaine addiction exist in Switzerland, despite the lack of a standard approach. Individualized plans combining pharmacological and psychotherapeutic strategies offer promising outcomes for cocaine dependence.

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Last Updated: May 19, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
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Published on: June 18, 2018

Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice
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Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice

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Area of Science:

  • Addiction medicine
  • Psychopharmacology
  • Clinical psychology

Background:

  • Switzerland has an estimated 100,000 occasional and 11,000 addicted cocaine users.
  • No single standard treatment protocol exists for cocaine addiction.

Purpose of the Study:

  • To review available pharmacological and psychotherapeutic treatment strategies for cocaine addiction.
  • To highlight the importance of individualized treatment plans.

Main Methods:

  • Review of current literature on cocaine addiction treatments.
  • Synthesis of evidence-based pharmacological and psychotherapeutic interventions.

Main Results:

  • Various helpful treatment options are available for cocaine addiction and its consequences.
  • Treatment success is enhanced when integrated into individualized, multi-component plans.

Conclusions:

  • Individualized treatment plans, incorporating diverse therapeutic elements, are crucial for managing cocaine dependence.
  • Longer treatment durations and multiple treatment sequences, in various settings, show promising results for cocaine-dependent patients.