Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurobehavioral studies in schizophrenia: implications for regional brain dysfunction.

R E Gur1, R C Gur, A J Saykin

  • 1Dept. of Psychiatry, University of Pennsylvania, Philadelphia 19104.

Schizophrenia Bulletin
|January 1, 1990
PubMed
Summary

Neurobehavioral methods offer insights into schizophrenia

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the relationships between Early Childhood Adversity, Social Cognition, and Aggression in a South African Study of People Living with Schizophrenia.

Schizophrenia research. Cognition·2025
Same author

Editorial Expression of Concern: Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia.

Molecular psychiatry·2025
Same author

Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health.

bioRxiv : the preprint server for biology·2025
Same author

Large-scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 children and adolescents.

Human brain mapping·2024
Same author

Remote assessment of the Penn computerised neurocognitive battery in individuals with 22q11.2 deletion syndrome.

Journal of intellectual disability research : JIDR·2024
Same author

Publisher Correction: Brain charts for the human lifespan.

Nature·2022

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Schizophrenia is a complex psychiatric disorder characterized by cognitive deficits.
  • Neuropsychological tests traditionally assess behavioral correlates of regional brain function.
  • Evidence suggests both frontal and temporal lobe dysfunction in schizophrenia.

Purpose of the Study:

  • To explore the utility of neurobehavioral methods in understanding schizophrenia's neurobiology.
  • To discuss methodological considerations for applying neuropsychological tests in schizophrenia research.
  • To highlight promising avenues for advancing the study of brain function in schizophrenia.

Main Methods:

  • Application of standard neuropsychological batteries.
  • Discussion of methodological challenges and considerations.
  • Introduction of behavioral imaging as a data integration approach.

Main Results:

  • Neurobehavioral methods provide valuable information on schizophrenia's neurobiology.
  • Systematic study of brain function is crucial for advancing the field.
  • Simultaneous neurobehavioral and physiological data acquisition shows promise.

Conclusions:

  • Neurobehavioral approaches are essential for elucidating brain function in schizophrenia.
  • Integrating diverse data streams, such as through behavioral imaging, is a key future direction.
  • Further systematic research is needed to fully understand the neurobiological underpinnings of schizophrenia.

Related Experiment Videos