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Autologous T cells on the attack against AML

Zwi N Berneman1

  • 1University of Antwerp.

Blood
|August 11, 2012
PubMed

In this issue of Blood, Greiner and colleagues describe how peptides derived from the mutated nucleophosmin 1 gene (NPM1(mut)) can elicit in vitro CD4(+) and CD8(+) T-cell responses in patients with acute myeloid leukemia, which can lead to antigen-specific lysis of leukemic blasts.

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