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Primary gastric Hodgkin's lymphoma
Ji-Han Jung1, Jihyun Kim, Gyeongsin Park
1Department of Hospital Pathology, The Catholic University of Korea St. Vincent Hospital, Suwon, Korea.
Journal of the Korean Surgical Society
|August 11, 2012
Summary
Primary gastric Hodgkin
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Gastric Hodgkin's lymphoma is an exceptionally rare malignancy.
- Primary involvement of the stomach by Hodgkin's lymphoma is exceedingly uncommon.
Observation:
- A 65-year-old woman presented with epigastric discomfort and reflux.
- Endoscopy revealed a smooth, protruding lesion in the gastric antrum.
- CT scan identified a 2.5 × 2.0 cm exophytic submucosal mass.
Findings:
- Microscopic examination showed a diffuse proliferation of large atypical lymphoid cells.
- Immunohistochemistry confirmed positivity for CD30, CD20, and CD79a.
- The diagnosis was established as primary gastric Hodgkin's lymphoma based on morphology and immunophenotype.
Implications:
- This case highlights the importance of considering rare diagnoses in gastric pathologies.
- Accurate diagnosis is crucial for appropriate patient management and treatment strategies.
- Further research may elucidate the specific pathogenesis and optimal therapeutic approaches for this rare condition.
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