Related Experiment Video
Updated: May 19, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
[Prevalence of uterine malformations and their impact on fertility]
Monika Gruszka1, Jan Wilczyński, Dorota Nowakowska
1Klinice Medycyny Matczyno-Płodowej i Ginekologii, III Katedry Połoznictwa i Ginekologii Uniwersytetu Medycznego w Łodzi, Polska.
Aim:
Uterine malformations belong to the most common congenital abnormalities within the female reproductive system. Their mean prevalence in the general population is 2-4%. The incidence of uterine malformation leads to impaired fertility and a number of obstetric complications such as threatening preterm delivery pelvic and transverse presentation, premature departure of amniotic fluid, intrauterine growth restriction, threatening rupture of the uterus, caesarean section. The aim of this review is to analyze the influence of an individual uterine malformation on female fertility.
Material And Methods:
The study involved 124 women hospitalized at Research Institute of the Polish Mothers Memorial Hospital in Lodz between the years 1994-2007. The patients were divided into 6 groups on the basis of the diagnosed defect.
Results And Conclusion:
In our study the most common defect was uterus bicornis, diagnosed in 46.7% of cases. The worst obstetric outcome was found among patients with septate uterus. The highest number of miscarriages and fertility problems occurs among those women. Nevertheless, there are positive data on the treatment of this defect. It would be recommendable to extend the diagnosis of the uterine malformations, especially in women with fertility problems, because early diagnosis and appropriate treatment allow to obtain satisfactory obstetric outcomes.
More Related Videos
05:46Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
Published on: January 17, 2019
06:49Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
Published on: April 7, 2023
Related Concept Videos
Teratogenicity
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of endometrial...
Infertility in Males
Disorders of the Female Reproductive System
Meiosis vs. Mitosis
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Oogenesis