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Updated: May 19, 2026

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening
08:14

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening

Published on: October 26, 2017

Are differentially expressed microRNAs useful in the diagnostics of malignant pleural mesothelioma?

Morten Andersen, Morten Grauslund, Marwa Muhammad-Ali

    APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
    |August 14, 2012
    PubMed
    Abstract

    No abstract available in PubMed .

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    MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
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