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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

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Related Experiment Videos

Adherence and medication management by the elderly.

Maria A Henriques1, Maria A Costa, José Cabrita

  • 1Department of Community Health Nursing, Lisbon Nursing College, Lisboa, Portugal. ahenriques@esel.pt

Journal of Clinical Nursing
|August 14, 2012
PubMed
Summary
This summary is machine-generated.

Elderly individuals manage medications through dynamic strategies, including daily routines and beliefs about drugs. Strong relationships with healthcare professionals, especially nurses, are crucial for effective medication adherence.

Related Experiment Videos

Area of Science:

  • Gerontology
  • Health Services Research
  • Nursing

Background:

  • Non-adherence to chronic medications is a significant challenge for the elderly.
  • Existing research has not fully addressed the complex, multidisciplinary nature of this problem.
  • Multiple, intricate factors contribute to medication non-adherence in older adults.

Purpose of the Study:

  • To explore the medication management strategies employed by elderly individuals living independently at home.
  • To understand the lived experiences and perspectives of older adults regarding their medication regimens.

Main Methods:

  • A descriptive qualitative research design was utilized.
  • Data were gathered through two focus groups with participants aged 65 and older.
  • Verbatim transcripts were analyzed to identify emergent themes and categories, culminating in a diagrammatic analysis.

Main Results:

  • Four primary categories emerged: living with medications, the act of taking medication, beliefs surrounding medications, and interactions with healthcare professionals.
  • Medication management was identified as a dynamic and complex process integrated into daily life.
  • Older adults perceive medication adherence as a consequence of aging, necessitating habit formation and routine adjustments.

Conclusions:

  • Understanding the elderly's perspective reveals medication management as an intricate process intertwined with daily living and aging.
  • The relationship with healthcare professionals, particularly nurses, is vital for effective medication management and adherence.
  • Further nursing research should focus on the quality of patient-provider relationships to enhance medication adherence in older populations.