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Related Experiment Video

Updated: May 19, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Immune-mediated interface dermatitis in a rhesus macaque.

L Makaron1, K Smith, C Bailey

  • 1Harvard Medical School, New England Primate Research Center, Southborough, MA 01772, USA. Leah_Makaron@hms.harvard.edu

Journal of Medical Primatology
|August 14, 2012
PubMed
Summary

This study details a rare case of autoimmune dermatitis in a rhesus macaque, presenting as palmoplantar hyperkeratosis. Long-term corticosteroid treatment effectively managed this immune-mediated skin condition in the primate.

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Last Updated: May 19, 2026

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Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques

Published on: April 22, 2010

Area of Science:

  • Veterinary Dermatology
  • Primate Immunology
  • Autoimmune Diseases

Background:

  • Autoimmune dermatitis, particularly interface dermatitis, is infrequently documented in nonhuman primate models.
  • Understanding autoimmune skin conditions in primates is crucial for comparative pathology and translational research.

Observation:

  • A rhesus macaque presented with clinical signs of palmoplantar hyperkeratosis.
  • The observed skin condition was diagnosed as idiopathic immune-mediated dermatitis.

Findings:

  • The case highlights a rare manifestation of autoimmune dermatitis in a nonhuman primate.
  • Long-term oral corticosteroid therapy proved effective in controlling the symptoms of immune-mediated dermatitis.

Implications:

  • This case contributes to the limited literature on autoimmune skin diseases in nonhuman primates.
  • Findings suggest corticosteroids as a viable therapeutic option for similar conditions in primates.
  • Further research into immune-mediated dermatopathies in nonhuman primates may offer insights into human dermatological conditions.