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Updated: May 19, 2026

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
Stability of intellectual functioning during maintenance electroconvulsive therapy
Lee E Wachtel1, Dirk M Dhossche, Irving M Reti
1Department of Psychiatry, Kennedy Krieger Institute, Johns Hopkins School of Medicine, 707 North Broadway Street, Baltimore, MD 21205, USA. Wachtel@kennedykrieger.org
Abstract:
We describe the stability of neuropsychologic testing in a 16-year-old boy with cerebellar dysgenesis who received 61 acute and maintenance electroconvulsive therapy treatments for malignant catatonia. Measures of nonverbal intelligence and visual memory before treatment onset and after 61 electroconvulsive therapy treatments indicated no evidence of decline in intellectual functioning and acute or delayed memory. This case offers further support for the safety and efficacy of maintenance electroconvulsive therapy in both pediatric and developmentally disabled populations.
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