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Related Concept Videos

Hydrogen Bonds01:04

Hydrogen Bonds

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A hydrogen bond is formed when a weakly positive hydrogen atom already bonded to one electronegative atom (for example, the oxygen in the water molecule) is attracted to another electronegative atom from another polar molecule, such as water (H2O), hydrogen fluoride (HF), or ammonia (NH3). The huge electronegativity difference between the H atom (2.1) and the atom to which it is bonded (4.0 for an F atom, 3.5 for an O atom, or 3.0 for an N atom), combined with the very small size of an H atom...
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Hydrogen Bonds00:26

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Hydrogen bonds are weak attractions between atoms that have formed other chemical bonds. One of these atoms is electronegative, like oxygen, and has a partial negative charge. The other is a hydrogen atom that has bonded with another electronegative atom and has a partial positive charge.
Hydrogen Bonds Control the World!
Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are unequally shared....
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Multivalent H-bonds for self-healing hydrogels.

Jiaxi Cui1, Aránzazu del Campo

  • 1Max-Planck-Institut für Polymerforschung, Ackermannweg 10, Mainz 55128, Germany.

Chemical Communications (Cambridge, England)
|August 14, 2012
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Summary
This summary is machine-generated.

Ureidopyrimidinones (UPy) enable the creation of injectable hydrogels with rapid self-healing properties. These dynamic crosslinkers allow materials to repair themselves quickly after damage.

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Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Biomaterials

Background:

  • Hydrogels are versatile materials with applications in drug delivery and tissue engineering.
  • Developing self-healing and injectable hydrogels remains a significant challenge in materials science.

Purpose of the Study:

  • To utilize ureidopyrimidinone (UPy) as a dynamic crosslinker for creating novel hydrogel materials.
  • To investigate the injectable and self-healing properties of UPy-based hydrogels.

Main Methods:

  • Synthesis of hydrogels using UPy as a reversible crosslinking agent.
  • Assessment of injectability through extrusion and flow studies.
  • Evaluation of self-healing capabilities via mechanical testing and microscopy after induced damage.

Main Results:

  • The UPy-crosslinked hydrogels demonstrated excellent injectability.
  • Rapid and efficient self-healing was observed in response to mechanical damage.
  • The dynamic nature of UPy crosslinks facilitated the repair process.

Conclusions:

  • UPy serves as an effective dynamic crosslinker for developing advanced hydrogels.
  • The resulting hydrogels possess desirable injectable and self-healing characteristics for potential biomedical applications.