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09:51
Purification of a High Molecular Mass Protein in Streptococcus mutans
Published on: September 14, 2019
Complete genome sequence of Streptococcus mutans GS-5, a serotype c strain
Saswati Biswas1, Indranil Biswas
1Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Journal of Bacteriology
|August 14, 2012
Summary
Streptococcus mutans causes dental caries and serotype c strains are most common. This study presents the full genome sequence of the widely used laboratory strain, S. mutans GS-5 (serotype c).
Area of Science:
- Microbiology
- Genomics
- Oral Health
Background:
- Streptococcus mutans is a primary cause of dental caries.
- It is the most cariogenic of all oral streptococci.
- Serotype c strains are the predominant S. mutans type in the human oral cavity.
Purpose of the Study:
- To present the complete genome sequence of Streptococcus mutans GS-5.
- To provide a genomic resource for a widely used laboratory strain of serotype c.
Main Methods:
- Whole-genome sequencing of S. mutans GS-5.
- Bioinformatic analysis of the genome sequence.
Main Results:
- The complete genome sequence of S. mutans GS-5 was determined.
- The genome provides a valuable resource for studying S. mutans biology and virulence.
Conclusions:
- The availability of the S. mutans GS-5 genome sequence facilitates further research into dental caries.
- This genomic data supports investigations into cariogenic mechanisms and potential therapeutic targets.
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