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Published on: December 16, 2013
Microwave assisted synthesis of amorphous magnesium phosphate nanospheres
Huan Zhou1, Timothy J F Luchini, Sarit B Bhaduri
1Department of Mechanical, Industrial and Manufacturing Engineering, University of Toledo, Toledo, OH, USA. Huan.Zhou@rockets.utoledo.edu
Abstract:
Magnesium phosphate (MgP) materials have been investigated in recent years for tissue engineering applications, attributed to their biocompatibility and biodegradability. This paper describes a novel microwave assisted approach to produce amorphous magnesium phosphate (AMP) in a nanospherical form from an aqueous solution containing Mg(2+) and HPO(4) (2-)/PO(4) (3-). Some synthesis parameters such as pH, Mg/P ratio, solution composition were studied and the mechanism of AMP precursors was also demonstrated. The as-produced AMP nanospheres were characterized and tested in vitro. The results proved these AMP nanospheres can self-assemble into mature MgP materials and support cell proliferation. It is expected such AMP has potential in biomedical applications.
