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Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
What is Monogastric Digestion?01:50

What is Monogastric Digestion?

The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.

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Related Experiment Video

Updated: May 19, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Eosinophilic gastroenteritis--a diagnostic enigma.

Urszula Simoniuk1, Chris McManus, Clement Kiire

  • 1Surgery Department, Southport General Hospital, Southport, UK. ula.daria@gmail.com

BMJ Case Reports
|August 15, 2012
PubMed
Summary

Eosinophilic gastroenteritis, a rare gastrointestinal disease, involves eosinophil infiltration. Consider this diagnosis in patients with atopy and abdominal symptoms, especially when asthma and ascites are present.

Area of Science:

  • Gastroenterology
  • Immunology
  • Pulmonology

Background:

  • Eosinophilic gastroenteritis is a rare gastrointestinal disorder characterized by eosinophil infiltration.
  • Its pathophysiology involves eosinophils affecting various GI tract parts and layers.
  • The condition has an approximate incidence of 1 in 100,000.

Observation:

  • Presents a case of eosinophilic gastroenteritis with predominant subserosal involvement.
  • This case is associated with asthma, ascites, and bilateral pleural effusion.
  • Highlights the co-occurrence of atopic conditions like asthma with gastrointestinal symptoms.

Findings:

  • Eosinophilic gastroenteritis should be considered in patients with atopy and gastrointestinal symptoms.
  • Diagnosis requires histological confirmation from the gastrointestinal tract and/or ascites.

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  • Other causes of eosinophilia, including parasitic infections and specific syndromes, must be excluded.
  • Implications:

    • Suggests a potential link between asthma and eosinophilic gastroenteritis, particularly with protein-losing gastroenteropathy.
    • Emphasizes the importance of considering eosinophilic gastroenteritis in patients presenting with both atopic conditions and abdominal complaints.
    • Underscores the need for differential diagnosis to rule out other causes of eosinophilia.