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Nutrition algorithms for infants with hypoplastic left heart syndrome; birth through the first interstage period
Julie Slicker1, David A Hehir, Megan Horsley
1Clinical Nutrition, Children's Hospital of Wisconsin, Milwaukee, WI 53201, USA. jslicker@chw.org
Insights
Infants with hypoplastic left heart syndrome often experience failure to thrive. Nutritional interventions may improve outcomes, but guidelines are lacking for these complex cases.
Area of Science:
- Pediatric Cardiology
- Neonatal Nutrition
- Congenital Heart Disease
Background:
- Failure to thrive is prevalent in infants with hypoplastic left heart syndrome (HLHS).
- Poor growth in HLHS infants is linked to adverse surgical and neurodevelopmental outcomes.
- The causes of growth failure in HLHS are multifactorial and not fully understood.
Purpose of the Study:
- To establish evidence-based nutritional recommendations for infants with single ventricle physiology.
- To address the lack of consensus guidelines for nutritional monitoring and intervention in this population.
- To provide guidance for healthcare professionals caring for infants with complex congenital heart disease.
Main Methods:
- A comprehensive literature review was conducted.
- Best nutrition practices from participating centers in the National Pediatric Cardiology Quality Improvement Collaborative were assessed.
- The Feeding Work Group synthesized findings to develop recommendations.
Main Results:
- Identified key nutritional challenges in infants with single ventricle physiology.
- Evaluated the evidence supporting various nutritional interventions.
- Developed recommendations with defined levels of evidence.
Conclusions:
- Nutritional intervention is a potential factor in improving outcomes for infants with HLHS.
- Standardized guidelines are needed for nutritional care in single ventricle physiology.
- Further research may refine nutritional strategies for this vulnerable population.
Abstract:
Failure to thrive is common in infants with hypoplastic left heart syndrome and its variants and those with poor growth may be at risk for worse surgical and neurodevelopmental outcomes. The etiology of growth failure in this population is multifactorial and complex, but may be impacted by nutritional intervention. There are no consensus guidelines outlining best practices for nutritional monitoring and intervention in this group of infants. The Feeding Work Group of the National Pediatric Cardiology Quality Improvement Collaborative performed a literature review and assessment of best nutrition practices from centers participating in the collaborative in order to provide nutritional recommendations and levels of evidence for those caring for infants with single ventricle physiology.
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