Related Experiment Video
Updated: May 19, 2026

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
Facial palsy in individuals with thalidomide embryopathy: frequency and characteristics
1Mun-H-Center Orofacial Resource Centre for Rare Diseases and Department of Speech Pathology, Institute of Neuroscience and Physiology, Sahlgrenska Academy at Gothenburg University, Sweden. lotta.sjogreen@vgregion.se
Background:
Earlier studies have shown that individuals with thalidomide embryopathy can have skeletal deformities, ear and eye aberrations, and facial palsy. This study aimed to survey the frequency and characteristics of facial palsy in this group of individuals.
Participants:
Thirty-one individuals with thalidomide embryopathy (age range, 45-47 years) and 25 healthy adults (age range, 41-56 years; mean age ± standard deviation, 49 ± 4.2 years).
Main Outcome Measures:
Voluntary facial movements, lip force and three-dimensional lip motion analysis.
Results And Conclusion:
Four of the thalidomide embryopathy individuals (13 per cent) had congenital facial palsy. All four had eye aberrations, three had ear anomalies and one had a limb anomaly. Individuals with thalidomide embryopathy without a clinical diagnosis of facial impairment had significantly weaker lips and more restricted lip mobility than healthy controls. This study contributes to the overall knowledge of thalidomide embryopathy by adding a description of how facial expression can be affected in this condition.
More Related Videos
08:03Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
10:23Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
Related Concept Videos
Teratogenicity
Prosopagnosia
Alterations in Muscle Tone ll
Neurulation
Secondary Spinal Cord Injury llI: Pathophysiology