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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Case for diagnosis. Atypical fibroxanthoma.
Mariana Hammerschmidt1, Luciana Menezes de Azevedo, Anelisa Ruaro
1Teaching Hospital, Federal University of Paraná, Curitiba, PR, Brazil. mari-hammer@hotmail.com
Anais Brasileiros De Dermatologia
|August 16, 2012
Summary
Atypical fibroxanthoma is a rare skin tumor in elderly individuals. Diagnosis requires differentiating it from other skin neoplasms, often using immunohistochemistry.
Area of Science:
- Dermatopathology
- Oncology
Background:
- Atypical fibroxanthoma (AFX) is an uncommon skin neoplasm.
- It primarily affects elderly individuals and occurs on sun-exposed skin.
Observation:
- Histological examination reveals bizarre neoplastic cells.
- Key features include marked pleomorphism, hyperchromatic nuclei, and abundant mitoses.
Findings:
- AFX is histologically classified as a malignant fibrous histiocytoma.
- Differential diagnosis from other cutaneous tumors is crucial.
Implications:
- Immunohistochemistry is frequently necessary for accurate AFX diagnosis.
- Diagnosis is often achieved through a process of exclusion.
