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Updated: May 19, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Case for diagnosis. Atypical fibroxanthoma
Mariana Hammerschmidt1, Luciana Menezes de Azevedo, Anelisa Ruaro
1Teaching Hospital, Federal University of Paraná, Curitiba, PR, Brazil. mari-hammer@hotmail.com
Abstract:
Atypical fibroxanthoma is a rare cutaneous tumor found mainly in elderly people on sun-exposed areas of the body. Histologically, atypical fibroxanthoma is considered a malignant fibrous histiocytoma with bizarre neoplastic cells, marked pleomorphism, hyperchromatic nuclei and abundant mitoses. It must be differentiated from other skin tumors, usually by immunohistochemistry, since its diagnosis is made by exclusion.
