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Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

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Nanomedicine: a primer for surgeons.

K K Y Wong1, X L Liu

  • 1Department of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China. kkywong@hkucc.hku.hk

Pediatric Surgery International
|August 16, 2012
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Summary

Nanomedicine, the application of nanotechnology to healthcare, offers innovative solutions for diagnostics, drug therapy, and regenerative medicine. Future developments promise personalized medicine and improved healthcare delivery.

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Area of Science:

  • Nanotechnology and its intersection with medicine, specifically nanomedicine.

Background:

  • Nanotechnology involves designing tools and devices at the nanoscale (1-100 nm).
  • Nanomedicine applies these nanoscale technologies to medical applications.

Purpose of the Study:

  • To review the fundamental principles of nanomedicine.
  • To explore experimental and clinical applications of nanomedicine.
  • To discuss safety considerations for nanomaterials in vivo.

Main Methods:

  • Review of existing scientific literature on nanomedicine.
  • Analysis of experimental and clinical studies.
  • Discussion of safety data for nanomaterials.

Main Results:

  • Nanomedicine encompasses applications in diagnostics, drug therapy, and regenerative medicine.
  • Safety issues related to the in vivo use of nanomaterials are a key consideration.
  • The field is rapidly advancing with significant research focus.

Conclusions:

  • Nanomedicine is poised to drive the development of personalized medicine.
  • This field is expected to significantly impact future healthcare delivery.
  • Continued research and safety assessments are crucial for clinical translation.