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Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination
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Meiotic recombinations within major histocompatibility complex of human embryos

Fulya Taylan1, Ender Altiok

  • 1Department of Molecular Biology and Genetics, Bogazici University, Istanbul, Turkey.

Immunogenetics
|August 16, 2012
PubMed

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Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I, duplicated...
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