Related Experiment Video
Updated: May 19, 2026

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
Published on: January 2, 2013
Modification of sodium, glucose, potassium, and osmolarity in packed red blood cells and fresh frozen plasma using a
Carrie Whittaker Striker1, Stacia Woldorf, David Holt
1Department of Cardiothoracic Surgery, Children's Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA. clstriker@cmh.edu
Abstract:
Massive transfusion with packed blood cells (PRBCs) or fresh frozen plasma (FFP) can result in dangerous complications including stroke, kidney failure, and cardiac arrest. A simple, bench top technique using a hemoconcentrator and dialysate solution is described to correct critical values of sodium, glucose, potassium, and osmolarity in PRBCs and FFP. Sodium, glucose, and osmolarity were corrected to normal or near normal values. Elevated potassium was reduced by 65%, but not completely normalized. A simple, bench top method for correcting dangerous abnormalities with PRBCs and FFP can be used to improve the safety of massive blood transfusion.
More Related Videos
Related Concept Videos
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Dialysis

