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Bacterial Gastroenteritis

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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...

Cholera

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...

Viral Hepatitis I: Introduction

Viral Hepatitis I: Introduction

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Viral Meningitis

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Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

Reservoir of Infection

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Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

Rous Sarcoma Virus (RSV) and Cancer

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Related Experiment Video

Updated: May 19, 2026

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus

Published on: January 28, 2019

[Rotavirus infection].

Hisashi Kawashima¹, Yasuyo Kashiwagi, Shigeo Nishimata

¹Department of Pediatrics, Tokyo Medical University.

Nihon Rinsho. Japanese Journal of Clinical Medicine

|August 17, 2012

Summary

Rotavirus infections cause severe diarrhea and critical illness globally, often requiring hospitalization. Vaccination and oral rehydration are key management strategies for this common viral gastroenteritis.

Area of Science:

Virology
Infectious Diseases
Pediatrics

Context:

Rotavirus is a leading cause of severe acute gastroenteritis worldwide.
Infections frequently lead to hospitalization (10%) due to serious complications.
Complications include severe dehydration, central nervous system diseases, sepsis, and renal insufficiency.

Purpose:

To summarize the epidemiology and clinical significance of rotavirus infections.
To highlight the importance of prevention and management strategies for rotavirus.
To inform healthcare providers about recommended treatment guidelines.

Summary:

Rotavirus is a ubiquitous virus responsible for acute gastroenteritis, with a significant proportion of cases resulting in severe illness and hospital admission.

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Common severe complications encompass dehydration, neurological issues, sepsis, and renal complications.

Effective rotavirus vaccinations are available, and international guidelines recommend oral rehydration solutions for treatment.

Impact:

Emphasizes the global health burden of rotavirus, particularly in vulnerable populations.
Underscores the critical role of vaccination in rotavirus prevention efforts.
Promotes adherence to established clinical management guidelines for improved patient outcomes.