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Updated: May 19, 2026
03:26
Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
[Neuromodulation as a treatment for overactive bladder syndrome]
Martijn A C Smits1, Tom A T Marcelissen, Philip E V van Kerrebroeck
1Maastricht Universitair Medisch Centrum, afd. Urologie, Maastricht, the Netherlands. martijn.smits@mumc.nl
Nederlands Tijdschrift Voor Geneeskunde
|August 17, 2012
Summary
Neuromodulation offers effective treatments for overactive bladder when conservative methods fail. Options like sacral neuromodulation and botulinum toxin injections provide alternatives, but potential complications require careful patient consideration.
Area of Science:
- Urology
- Neurology
- Minimally Invasive Surgery
Context:
- Overactive bladder syndrome often requires advanced treatments when conservative management proves insufficient.
- Sacral neuromodulation has evolved into a minimally invasive procedure with established long-term efficacy.
- Persistent challenges include potential complications like pain and diminished treatment effectiveness.
Purpose:
- To review the current landscape of neuromodulation therapies for overactive bladder.
- To highlight emerging and established neuromodulation techniques, including their indications and outcomes.
- To emphasize the importance of personalized treatment selection based on efficacy, safety, and patient-specific factors.
Summary:
- Neuromodulation, including sacral neuromodulation and posterior tibial nerve stimulation, provides alternatives for overactive bladder refractory to conservative care.
- Intravesical botulinum neurotoxin injection is now a recognized component of the overactive bladder treatment algorithm.
- Treatment decisions necessitate a thorough evaluation of potential side effects, complications, and long-term effectiveness.
Impact:
- Expanded therapeutic options for patients with refractory overactive bladder syndrome.
- Improved understanding of the risk-benefit profiles of various neuromodulation techniques.
- Informed clinical decision-making for optimizing overactive bladder management.
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