Related Experiment Video
Updated: May 19, 2026
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Changes in body weight and adiposity predict periodontitis progression in men
1Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA. agorman@Lifespan.org
Journal of Dental Research
|August 17, 2012
Summary
Rapid weight gain and increased waist circumference are linked to periodontitis progression in men. Tracking adiposity changes may help predict the risk of this common gum disease.
Area of Science:
- Periodontology
- Obesity research
- Preventive medicine
Background:
- Obesity is a growing public health concern.
- Existing research on obesity and periodontal disease is primarily cross-sectional.
- Longitudinal data on the impact of weight changes on periodontal health is limited.
Purpose of the Study:
- To investigate the association between changes in body weight, waist circumference, and arm fat area with periodontitis progression.
- To determine if anthropometric measures can predict the risk of periodontal disease advancement.
Main Methods:
- Prospective cohort study of 893 non-diabetic men over four decades (VA Dental Longitudinal Study).
- Measurement of probing pocket depth (PPD) by calibrated examiners.
- Use of repeated-measures generalized linear models to analyze PPD events and disease progression, adjusting for confounders.
Main Results:
- Overweight men with rapid weight gain (>0.19 kg/yr) showed significantly more PPD events than those with minimal weight gain (≤-0.05 kg/yr).
- Increased waist circumference (>0.14-0.39 cm/yr or >0.39 cm/yr) was associated with more PPD events in overweight men.
- In normal-weight men, an increase in arm fat area correlated with periodontitis progression.
Conclusions:
- Weight gain and increased waist circumference are significant risk factors for periodontitis progression in men.
- Changes in easily measured anthropometric indicators like weight and waist circumference may aid in predicting periodontal disease risk.
- Further research into the link between adiposity and periodontal health is warranted.
Related Concept Videos
01:27The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
01:15Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
01:30Coronary Artery Disease I: Introduction
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...