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[Physiologic and pathologic age related changes in the small intestine].

E O Riecken¹, T Balzer

¹Abteilung für Innere Medizin mit Schwerpunkt Gastroenterologie, Freien Universität Berlin.

Fortschritte Der Medizin

|November 30, 1990

Summary

Aging causes mild changes in small intestine function, particularly affecting carbohydrate, vitamin D, and calcium absorption. These changes may impact osteoporosis development and treatment, though the small bowel

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Area of Science:

Gerontology and gastrointestinal physiology.
Investigating age-related changes in organ systems.

Context:

The small bowel exhibits functional reserve capacity.
Known age-related functional impairments include carbohydrate, vitamin D, and calcium absorption.
These absorptive changes may relate to osteoporosis pathogenesis.

Purpose:

To review the functional and morphological changes in the aging small bowel.
To establish a morphological correlate for known functional disorders.

Summary:

Aging leads to mild small bowel functional impairments, notably in nutrient absorption.
Vitamin D and calcium absorption changes are significant for osteoporosis.
Functional reserve capacity compensates for many age-related disturbances.

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No morphological basis for these functional changes has been identified.

Impact:

Highlights potential links between small bowel function and osteoporosis.
Suggests areas for future research into age-related gastrointestinal changes.
Informs understanding of nutrient absorption in aging populations.