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1Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.
Abstract:
Decisions about what, when and how much to eat are made by the brain, though these choices can be strongly influenced by the hedonic and rewarding properties of sweet or fatty foods. The rumbling before and the fullness after eating tells us that the gut also has an important role in the initiation and termination of feeding. Gut-derived peptides continually convey homeostatic information to the brain to guide feeding. These circulating signals can also modify the pleasure and reward associated with food.
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