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Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point

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Supratentorial pure cortical ependymoma.

Satoshi Nakamizo¹, Takashi Sasayama, Takeshi Kondoh

¹Department of Neurosurgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia

|August 18, 2012

Summary

We report an extremely rare case of cerebral cortical ependymoma in a young woman presenting with seizures. Complete surgical resection led to seizure freedom and no recurrence during follow-up.

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Area of Science:

Neuro-oncology
Neuropathology

Background:

Ependymomas typically arise within the ventricles of the brain.
Supratentorial extraventricular ependymomas are uncommon, with cortical locations being exceptionally rare.

Observation:

A 20-year-old female presented with generalized seizures.
Imaging revealed a calcified intracortical mass in the left precentral gyrus.
The 12-mm mass showed mild, heterogeneous enhancement post-gadolinium.

Findings:

Histopathology confirmed World Health Organization grade II ependymoma with perivascular pseudorosettes.
Immunohistochemistry was positive for glial fibrillary acidic protein, S-100, and epithelial membrane antigen.
Complete tumor resection was achieved without neurological deficit.

Implications:

This case highlights the possibility of rare supratentorial cortical ependymomas.
Successful surgical management can lead to favorable outcomes, including seizure control and long-term remission.
Further research into the specific characteristics and optimal treatment of extraventricular ependymomas is warranted.