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Updated: May 19, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Extra-articular diffuse-type giant cell tumour of the temporomandibular joint
M De Benedittis1, M Turco, M Petruzzi
1Ospedale Regionale Generale F. Miulli Strada Prov., 127 Acquaviva - Santeramo Km. 4,100, 70021 Acquaviva delle Fonti (BA), Italy. micdeben2002@libero.it
Abstract:
Diffuse-type giant cell tumour (DTGCT) is a benign but destructive proliferative disorder of the synovium of joint capsules, tendons and bursae. Lesions originating from the articular synovium may grow intra-articularly or expand widely extra-articularly. Rare cases may develop only in peri-articular tissues. Temporomandibular joint (TMJ) involvement is exceptional and only two cases of purely extra-articular TMJ-DTGCT have been reported. The authors report an additional case of extra-articular TMJ-DTGCT. The clinical features, histopathological characteristics, imaging modalities and diagnostic methods for DTGCT are discussed together with a literature review based on the clinical aspects of TMJ involvement.
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