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Updated: May 19, 2026
03:22
Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
Published on: March 1, 2024
Pulmonary coccidiomycosis in New Delhi, India
J K Oberoi1, C Wattal, P K Aggarwal
1Department of Clinical Microbiology and Immunology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India.
Infection
|August 18, 2012
Summary
Coccidioidomycosis, a fungal infection, requires high suspicion in non-endemic areas. Early diagnosis and treatment with fluconazole are crucial for patient recovery.
Area of Science:
- Mycology
- Infectious Diseases
- Pulmonology
Background:
- Coccidioidomycosis is endemic to the Western Hemisphere.
- Diagnosis in non-endemic areas necessitates a high index of suspicion and exposure history.
- Fungal lung infections can mimic other respiratory illnesses.
Observation:
- A 65-year-old male presented with fever, cough, and malaise.
- Chest X-ray revealed left lower lobe consolidation, bilateral nodular lesions, and mediastinal lymphadenopathy.
- The patient had a recent 6-month history of living in Arizona, USA.
Findings:
- Pulmonary coccidioidomycosis was confirmed by isolating Coccidioides spp. from bronchoalveolar lavage and lung biopsy.
- Gene sequencing identified the isolate as Coccidioides posadasii.
- The patient responded well to fluconazole treatment.
Implications:
- Highlights the importance of considering endemic fungal infections in patients with relevant travel history.
- Demonstrates the effectiveness of prompt diagnosis and antifungal therapy.
- Emphasizes the role of molecular methods in accurate pathogen identification.
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