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[Fine needle biopsy in diagnosis of cervical lymph node changes]
C Reisser1, K Goerttler, G Feichter
1Universitäts-HNO-Klinik Heidelberg.
HNO
|November 1, 1990
Summary
Fine needle aspiration biopsy is a useful screening tool for cervical lymph node disease, confirming clinical suspicion of malignancy. While it has a notable false-negative rate, it aids diagnosis when interpreted alongside other clinical information.
Area of Science:
- Oncology
- Pathology
- Cytopathology
Context:
- Cervical lymph node disease diagnosis
- Evaluation of fine needle aspiration biopsy (FNAB) utility
- 1983-1989 study period with 495 outpatients
Purpose:
- To examine the validity and specificity of FNAB in diagnosing cervical lymph node disease
- To assess the diagnostic accuracy of FNAB compared to histology and clinical history
Summary:
- 495 outpatients underwent FNAB; 107 smears were unusable.
- Tumor cells identified in 124/388 usable smears, with 117 confirmed by histology/clinical history.
- 14% false-negative rate observed, particularly in patients with prior therapy or malignant lymphoma.
Impact:
- FNAB is a valuable screening method for cervical lymph node disease
- FNAB can confirm clinical suspicion of malignancy but cannot disprove it
- Highlights the importance of considering prior treatments and specific diagnoses like lymphoma when interpreting FNAB results