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Peroral Endoscopic Myotomy for Esophageal Achalasia by HybridKnife: A Case Report

Ping-Hong Zhou1, Ming-Yan Cai, Li-Qing Yao

  • 1Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Case Reports in Gastrointestinal Medicine
|August 18, 2012
PubMed

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Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...