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Updated: May 19, 2026

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Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
Published on: October 30, 2015
EPR studies on Fcgamma receptor-mediated changes in lymphocyte membrane
Rajesh K Gupta1, Abhay H Pande, Sumati
1School of Life Sciences, Devi Ahilya Vishwavidyalaya, Vigyan Bhawan, Khandwa Road Campus, Indore 452 001 (MP), India.
Indian Journal of Biochemistry & Biophysics
|August 21, 2012
Abstract:
Biophysical evidence has been presented for the interaction of human lymphocyte membrane Fc receptors with aggregated IgG by severely restricting the rotational mobility of the cell surface proteins, as well as membrane lipids. Decrease in membrane fluidity was more prominent with aggregated IgG since the multivalency of Fc regions in aggregated IgG cross-linked cell surface Fc receptor.

