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Updated: May 19, 2026

Genetic Incorporation of Biosynthesized L-dihydroxyphenylalanine (DOPA) and Its Application to Protein Conjugation
Published on: August 24, 2018
Absorption spectral study of 3, 4-dihydroxy phenyl alanine (DOPA) with Nd (III) in aqueous medium
Prashant N Bhatt1, Trupti V Pathak, Jignasu P Mehta
1Department of Chemistry, Bhavnagar University, Bhavnagar 364 002, India. pnbchem@hotmail.com
Abstract:
Spectroscopic properties of Nd (III)-DOPA in aquated organic solvents are investigated through absorption difference and comparative absorption spectroscopy involving 4f-4f transitions. The change in coordination in different conditions is observed from the absorption intensity analysis when Nd (III) interacts with DOPA. The interaction induced substantial changes in the intensities of 4f-4f bands and their perturbation was reflected through oscillator strength Judd-Ofelt intensity (Tlamda) parameters. It is suggested that the changes in the oscillator strengths of different 4f-4f bands and Judd-Ofelt intensity (Tlamda) parameters can be used to predict in vivo intracellular complexation of DOPA with Ca(II) through Nd (III)-DOPA absorption spectral studies in-vitro as both Nd (III) and Ca(II) have unique similarity in their coordination behaviour.
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