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Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

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U Clips for arteriovenous anastomosis: a pilot, randomized study.

Stuart Robert Walker¹

¹Department of Vascular and Endovascular Surgery, Royal Hobart Hospital, Hobart, Tasmania, Australia. stuart.walker@dhhs.tas.gov.au

ANZ Journal of Surgery

|August 21, 2012

Summary

A new nitinol U-clip for arteriovenous anastomosis showed no significant benefit over traditional Prolene sutures in a pilot study. This technique did not improve fistula success rates for hemodialysis access.

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A Modified Technique for Arteriovenous Fistula Construction in Rabbits

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Published on: February 10, 2023

Area of Science:

Vascular Surgery
Nephrology
Biomedical Engineering

Background:

Arteriovenous fistulas are crucial for hemodialysis access.
Surgical techniques for creating these fistulas aim to optimize patency and function.
Novel devices are being developed to improve anastomosis procedures.

Purpose of the Study:

To evaluate a new nitinol U-Clip device for creating arteriovenous anastomoses.
To compare the efficacy of the U-Clip technique against conventional Prolene suturing.

Main Methods:

A pilot, randomized, blinded trial (NCT00829153) was conducted.
Thirty-one patients undergoing autologous arteriovenous fistula creation were included.
Patients were randomized to either U-Clip or 6/0 Prolene anastomosis.

Main Results:

The primary outcome (three successful dialysis treatments) was achieved in 42% of the Prolene group (8/19) and 58% of the U-Clip group (7/12).
The difference in success rates between the two groups was not statistically significant (P=0.379).

Conclusions:

The nitinol U-Clip technique did not demonstrate a significant advantage over the traditional continuous Prolene anastomosis.
Further research may be needed to explore potential benefits or modifications of the U-Clip device.